Explainer: New, Highly Mutated Lineage Of Virus That Causes Covid

Explainer: New, Highly Mutated Lineage Of Virus That Causes Covid


It is too soon to know whether BA.2.86 will cause more-severe illness.

The World Health Organization and the U.S. Centers for Disease Control and Prevention are tracking a new, highly mutated lineage of the virus that causes COVID-19.

Six cases in four countries have been detected since late July. Scientists are keeping an eye on the new lineage, named BA.2.86, because it has 36 mutations that distinguish it from the currently-dominant XBB.1.5 variant.

So far there is no evidence that BA.2.86 spreads faster or causes more serious illness than previous versions. The CDC said its advice on protecting yourself from COVID remains the same.

What is new about COVID?

COVID infections and hospitalizations have been rising in the U.S., Europe and Asia, with more cases in recent months attributed to the EG.5 “Eris” subvariant, a descendant of the Omicron lineage that originally emerged in November 2021.

Over the past few days, public health authorities have documented one case each of BA.2.86 in the United States, the UK, and Israel, and three cases in Denmark.

What do scientists say about BA.2.86?

BA.2.86 stems from an “earlier branch” of the coronavirus, so it differs from the variant targeted by current vaccines, explained Dr. S. Wesley Long, medical director of diagnostic microbiology at Houston Methodist Hospital.

He said it remains to be seen whether BA.2.86 will be able to out-compete other strains of the virus or have any advantage in escaping immune responses from prior infection or vaccination.

But many countries have drastically reduced testing of patients and their efforts to analyze the genomes of the viruses causing new COVID cases. In that situation, the trajectory of BA.2.86 “doesn’t look good right now,” given the speed at which new cases are being identified, said Dr. Eric Topol, a genomics expert and director of the Scripps Research Translational Institute in La Jolla, California.

Its many mutations make BA.2.86 “radically different in its structure” compared to earlier variants, Topol said.

The main question, he added, is whether BA.2.86 will turn out to be highly transmissible.

Do the new variants make people sicker?

U.S. emergency department visits and hospitalizations for COVID remain low, but have been rising since early July, according to data on the CDC website. So far, however, doctors have been reporting that patients seen in recent weeks, as the Eris variant has been spreading, are not as sick as those they treated during earlier waves of the pandemic.

Wider spread of BA.2.86 would likely cause more illness and death in vulnerable populations, Topol said.

It is too soon to know whether BA.2.86 will cause more-severe illness.

“Based on the available evidence, we do not yet know what risks, if any, (BA.2.86) may pose to the public’s health beyond what has been seen with other currently circulating lineages,” a CDC spokesperson said.

Will vaccines protect against new variants?

Due to the waning of the pandemic, it may have been a year or more since many people were either previously infected or vaccinated against COVID.

“The vaccine is still going to provide you great defense against illness and death,” Long said.

Updated COVID booster shots now being developed have been designed to target the Omicron subvariant XBB.1.5.

Moderna said preliminary trial data suggest its latest version of the vaccine shows promise against Eris and a related variant called Fornax, which has begun to circulate in the U.S.

Pfizer Inc has said its updated COVID-19 shot showed neutralizing activity against the Eris subvariant in a study conducted on mice.

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)



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Lucy Letby: From Nurse To Child Murderer

Lucy Letby: From Nurse To Child Murderer


Letby was accused of harming 17 babies.

The trial of nurse Lucy Letby, who was on Friday found guilty of murdering seven babies and attempting to kill another six, was one of the longest in British criminal history. 

Here are some of the key points.

Lucy Letby 

Originally from Hereford in western England, Letby studied nursing at the University of Chester.  “I have always wanted to work with children,” she told Manchester Crown Court during her trial.

Letby graduated in 2011 and started full-time at the Countess of Chester Hospital the following year, joining the neo-natal unit.  In 2015, she qualified to work on intensive care babies, which would have allowed her to work with the sickest babies in the unit. 

She had an active social life, attended salsa classes, travelled and went to the gym, the court heard. 

Victims

Letby was accused of harming 17 babies, some of them just days old, between June 2015 and June 2016. In the majority of cases she is believed to have injected them with air but prosecutors also accused her of introducing insulin or too much milk.

The jury found her guilty of murdering seven babies and attempting to kill six others on the 22nd day of deliberations. She was found not guilty on two counts of attempted murder and the jury could not reach a verdict on six attempted murder charges.

Among her victims were a twin brother and sister and two triplet boys. The names of the babies were not allowed to be reported and are instead referred to as baby A through to Q.

Letby is said to have on several occasions carried out Facebook searches for the parents of babies that she allegedly attacked. She said she would look up to people when she was thinking about them. 

Suspicion  

The neo-natal unit saw a “significant” increase in the number of babies dying and suffering serious collapses during the period in question, prosecutor Nick Johnson said at the trial. 

A search for the cause revealed “one common denominator” and that was Letby, he added.  Following the deaths of two triplets in June 2016, Letby was removed from the neo-natal unit and placed on clerical duties.

“It was life-changing, in that moment I was taken away from the support system I had on the unit, I was put in a role I did not enjoy and I had to pretend it was voluntary,” Letby told the court. 

Letby said it was “devastating” when she received a letter from the Royal College of Nursing that blamed her for the deaths of the babies. She told the court she was prescribed anti-depressants, which she is still taking, and admitted to having thoughts of harming herself.

Arrests And Search  

Letby was arrested and released twice, with her first arrest in July 2018. On her third arrest in 2020, she was formally charged and placed into custody. 

Among the items found during a search of Letby’s home was a Post-it note on which she wrote: “I don’t deserve to live. I killed them on purpose because I’m not good enough to care for them”. “I am evil I did this,” she wrote in capital letters.

Letby claimed the note was written around the time she was removed from the neo-natal unit, leaving her feeling like she “had done something wrong”.

The prosecution said police also found a “large quantity” of hospital paperwork relating to several of the children that she is accused of harming.

Letby’s Defence 

Representing Letby, lawyer Ben Myers said it’s important that “blame is not heaped on that woman”, while there may be others who made mistakes or systems that had failed. 

He described Letby as a “dedicated nurse”, who “cared deeply” for the babies and their families. 

Mr Myers also said there was “no direct evidence” of Letby committing the crimes and pointed to the condition of the babies at birth, saying they were “clinically fragile”. He also said the unit had staffing issues at the time.

Letby has repeatedly denied hurting or wanting to hurt the babies, saying “that’s completely against what being a nurse is”. She had suggested that a “gang” of four hospital consultants had conspired to pin the blame on her “to cover failings at the hospital”.

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)



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Ladakh BJP Veteran, 74, Pays Price After Son Elopes With Buddhist Woman

Ladakh BJP Veteran, 74, Pays Price After Son Elopes With Buddhist Woman


A BJP leader in Ladakh was expelled from the party after his son eloped with a Buddhist woman

Leh:

The BJP in Ladakh has expelled a senior leader after his son eloped with a Buddhist woman and married her.

Nazir Ahmad, 74, state vice president of the Ladakh BJP, has been expelled from the primary membership of the party after his son reportedly eloped with a Buddhist woman more than a month ago.

In a statement, the BJP’s Ladakh unit said action against its senior leader was taken after he was given an “opportunity to clarify about his involvement in the sensitive issue of elopement of a Buddhist girl by his son.”

The expulsion order was issued by Ladakh BJP chief Phunchok Stanzin after an executive meeting of the party on Wednesday.

The BJP in a statement said elopement is “unacceptable to all religious communities in Ladakh as it jeopardises communal harmony and unity among the people of the region”.

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The couple married more than a month ago and since then they are untraceable.

The expelled BJP leader said his family was also against the marriage of his son, Manzoor Ahmad, with the Buddhist woman, and he has no idea where they are staying for the past one month.

Mr Ahmad, a veteran BJP loyalist, said he was away on Hajj pilgrimage in Saudi Arabia when his son and the woman married in a court.

“My son is 39 years old and the woman he married is 35. I believe both had performed nikah way back in 2011. Last month, they performed court marriage when I was away on Haj pilgrimage,” the expelled BJP leader said.

Mr Ahmad said that before he was expelled from the party, he was told to resign as he was unable to trace his son.

“I don’t know why they blame me for the marriage of my son when our whole family was against it. I have tried to trace him. I visited Srinagar and several other places to find him,” Mr Ahmad said.



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BJP Names Chhattisgarh, Madhya Pradesh Candidates, A First Before Poll Dates

BJP Names Chhattisgarh, Madhya Pradesh Candidates, A First Before Poll Dates



New Delhi:

The BJP today announced first lists of candidates for Assembly polls in Madhya Pradesh and Chhattisgarh due later this year. This is the first time the BJP has announced names of candidates even before the Election Commission of India announces the poll dates.

The party has announced 21 candidates for the 90-member Chhattisgarh Assembly and 39 for the 230-member Madhya Pradesh house.

The announcement comes a day after Prime Minister Narendra Modi chaired a meeting of the BJP’s central election committee, the party’s decision-making body for selection of candidates and preparation of poll strategies.

The BJP leadership’s unprecedented decision to announce candidates’ names well in advance appears to be aimed at identifying friction within the ranks and resolve issues well in advance.

Following the poll setback in Karnataka earlier this year, the party is in no mood for another debacle. Chhattisgarh and Madhya Pradesh are among five states going to polls later this year, along with Rajasthan, Telangana and Mizoram.

Out of these, Chhattisgarh, Rajasthan and Madhya Pradesh are ruled by Opposition forces. In Mizoram, BJP’s ties with ally and ruling party Mizo National Front are strained in the wake of the Manipur unrest. And in Madhya Pradesh, a neck-to-neck fight is expected between the BJP and the Congress.

One highlight in Chhattisgarh list is the name of Vijay Baghel, Lok Sabha MP from Durg. A former MLA from Patan, he has been fielded from the same seat this time. The names of former Chief Minister Raman Singh and other senior party leaders are missing from the first list.

In Madhya Pradesh, the names of Chief Minister Shivraj Singh Chouhan and prominent ministers are not in the first list of candidates.

The BJP’s Chhattisgarh list comprises five women, 10 candidates from Scheduled Tribes and one from the Scheduled Castes category. For Madhya Pradesh, the party has chosen five women, eight Scheduled Caste candidates and 13 Scheduled Tribes candidates.



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Chest Measurement Criterion For Women For Any Post “Outrageous”: Rajasthan High Court

Chest Measurement Criterion For Women For Any Post “Outrageous”: Rajasthan High Court


The court observed that the criterion is absolutely arbitrary. (Representational)

Jodhpur:

The Rajasthan High Court has denounced the criterion of chest measurement to gauge the lung capacity of female candidates during physical examination in recruitment process for foresters “or any other post”, saying it is absolutely arbitrary and outrageous and dents a woman’s dignity.

It also directed the state authorities to seek opinions of experts to explore the possibility of any alternative means to determine the desired level of lung capacity “to avoid this unwarranted humiliation of women candidates”.

Justice Dinesh Mehta made the observation while deciding a petition by three female candidates challenging their disqualification on the parameter of chest measurement despite clearing the Physical Efficiency Test for the post of Forest Guard.

The court preferred not to intervene in the recruitment process, which had already taken place, but stated “some deliberation is necessary about the very requirement of chest measurement for the female candidates, may it be for the recruitment of Forest Guard or Forester or any other post”.

The size of the chest and its expansion in the case of a female candidate may not necessarily be a pointer of physical fitness and a litmus test of the lungs’ capacity, the judge observed in the August 10 order.

“Even if it be so, such measurement impinges upon or intrudes on the privacy of a female. Apart from being irrational, prescribing such criterion disrupts the dignity, bodily autonomy and mental integrity of a woman”, the court stated in its order.

The court observed that the criterion is absolutely arbitrary and outrageous and a clear dent on a woman’s dignity and right to privacy guaranteed under Articles 14 and 21 of the Constitution of India.

The petitioners have told the court that their measurement was more than required after which the high court sought a report from the medical board of AIIMS.

The report, however, stated that two candidates’ chest measurements were less than required in the “normal condition” while one of them had chest measurement less than required in the “expanded condition”.

Based on this report, the court rejected their petitions and upheld the decision of the recruiting agency to disqualify them, but objected to the use of chest measurement among female candidates.

A copy of the order was marked to the state chief secretary, the secretary of the forest department and the secretary of the department of personnel to have a relook into this criterion.

It asked them to solicit the opinion of experts to explore the possibility of alternative means to determine the desired level of lung capacity.

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)



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What Chandrababu Naidu Said On Joining NDA Alliance Again

What Chandrababu Naidu Said On Joining NDA Alliance Again


Chandrababu Naidu further said that his role is very clear for national politics in 2024.

Visakhapatnam:

As there is a buzz about Telugu Desam Party (TDP) joining the National Democratic Alliance (NDA) once again, Former Chief Minister of Andhra Pradesh and the party President Chandrababu Naidu on Tuesday said that he will talk about it at the ‘right time’.

On being asked about his plan to join the NDA, Mr Naidu said ‘it is not the right time’.

“It’s not the time to talk about joining the NDA government. I will talk about this at the right time,” he said while talking to ANI.

Mr Naidu was speaking to ANI, after releasing the Vision-2047 document at a programme organised in this Port City on Tuesday evening.

One of the founders of the National Democratic Alliance (NDA) – the Chandrababu Naidu-led Telugu Desam Party (TDP) had left in protest against the Centre’s refusal to give special status to Andhra Pradesh.

Mr Naidu further said that his role is very clear for national politics in 2024.

“My priority is Andhra Pradesh. It’s my big agenda. I will prepare for the rebuilding and reconstruction of the state,” the TDP chief said.

Responding to the Amaravati capital issue,Mr Naidu said, “You (CM Jagan Mohan Reddy) are sitting in assembly. You are sitting in the secretariat. Where are you conducting the cabinet meeting? Is it temporary? What Jagan Mohan Reddy is talking rubbish. For the last ten years, they have been functioning. Everything got ready. We planned the world-class capital for Andhra Pradesh. I planned systematically one of the best ecosystems for Hyderabad for nine years.”

Notably, the unified state of Andhra Pradesh was bifurcated into Andhra Pradesh and Telangana in June 2014.

As per the AP Reorganisation Act, Hyderabad became the capital of Telangana, and Andhra Pradesh had to find itself a new capital within ten years; until then, Hyderabad would serve as the capital for both states.

In January this year, Jagan Mohan had announced that Visakhapatnam is going to be the capital with no mention of it in any state assembly discussion or on any official documents.

Later, the YS Jagan Mohan Reddy-led government had decided to make three capitals in different cities of the State in order to ensure development in all parts of the state.

Earlier on Tuesday evening, Chandrababu Naidu paid tribute to the statue of the former chief minister, the late NT Rama Rao, on Beach Road.

(Except for the headline, this story has not been edited by NDTV staff and is published from a syndicated feed.)

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